Inflammation is a physiological process of the organism, defensive and necessary, which occurs in the face of very diverse aggressions, being crucial for the defence and repair of tissue. It really is a frequent situation and at practically all times we have some inflammatory process, often imperceptible, which responds to a specific cause with the aim of re-establishing harmony and function. However, on certain occasions, inflammation persists and becomes chronic, without an obvious cause. This chronic, low-grade inflammation can present diffuse or misleading symptoms and become a pathology that impairs quality of life, increases the risk of disease and, in some cases, increases mortality.<\/p>\n\n\n\n
OA is a chronic disorder <\/a>which, associated with inflammation, alters cartilage, subchondral bone and surrounding tissues.<\/p>\n\n\n\n To combat chronic inflammation, it is essential to treat the underlying cause when it is known. However, drugs such as non-steroidal anti-inflammatory drugs (NSAIDs), corticosteroids, etc. are used.<\/p>\n\n\n\n More than two decades ago, SPMs were discovered, which are mediators of the resolution of inflammation produced naturally by the body itself. Omega-3s provide the raw material for the production of SPMs in our bodies.<\/p>\n\n\n\n At the International Osteoarthritis Foundation (OAFI), we actively participate in scientific studies such as the study GAUD\u00cd<\/a>, a study that validated the efficacy of SPMs, natural derivatives of Omega-3s, showing that they reduce pain and improve the functionality and quality of life of patients with osteoarthritis.<\/p>\n\n\n\n You can find more details in the article just published in issue 197 of the magazine New Medical Economics<\/a> which you will find below:<\/p>\n\n\nSPMs and Gaud\u00ed<\/h2>\n\n\n\n